British Journal of Medical & Surgical Urology
Volume 3, Issue 5 , Pages 190-193, September 2010

When should radiotherapy be used after radical prostatectomy? The RADICALS-RT Trial

  • Christopher C. Parker

      Affiliations

    • Royal Marsden Hospital, Sutton, Surrey, United Kingdom
  • ,
  • Noel W. Clarke

      Affiliations

    • Hope Hospital and Christie Hospital, Manchester, United Kingdom
  • ,
  • Howard Kynaston

      Affiliations

    • University Hospital of Wales, Cardiff, United Kingdom
  • ,
  • Matthew R. Sydes

      Affiliations

    • MRC Clinical Trials Unit, Cancer Group, London, United Kingdom
    • Corresponding Author InformationCorresponding author. Tel.: +44 020 7670 4798.

Received 19 March 2010; accepted 21 April 2010.

Abstract 

Despite two recent trials of the role of early radiotherapy following radical prostatectomy, there remains no consensus as to best practice and clinicians tend to base their decisions around MDT discussion and pathological risk factors. This paper develops the argument for international Intergroup trial, RADICALS-RT, which is now recruiting, and which is our opportunity to resolve this important issue.

Keywords: Clinical trial, Prostate cancer, Radiotherapy, Prostatectomy, Survival, Collaboration, Engagement, Urologists, Oncologists, Early, Deferred

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PII: S1875-9742(10)00122-9

doi:10.1016/j.bjmsu.2010.04.007

British Journal of Medical & Surgical Urology
Volume 3, Issue 5 , Pages 190-193, September 2010