British Journal of Medical & Surgical Urology
Volume 2, Issue 2 , Pages 73-78 , March 2009

The effect of intravesical single-dose Mitomycin C in recurrent superficial bladder cancer

  • Benjamin R. Grey

      Affiliations

    • Department of Urology, Stepping Hill Hospital, Stockport NHS Foundation Trust, Poplar Grove, Stockport SK2 7JE, UK
    • Department of Urology, Royal Blackburn Hospital, East Lancashire Hospitals NHS Trust, Haslingden Road, Blackburn BB2 3HH, UK
    • Corresponding Author InformationCorresponding author at: Specialist Registrar in Urology, Department of Urology, Royal Blackburn Hospital, East Lancashire Hospitals NHS Trust, Haslingden Road, Blackburn BB2 3HH, UK. Tel.: +44 125 426 3555; fax: +44 1254 736114.
    • ,
  • Joanne Butler

      Affiliations

    • Department of Urology, Stepping Hill Hospital, Stockport NHS Foundation Trust, Poplar Grove, Stockport SK2 7JE, UK
    • ,
  • Richard A. Darling

      Affiliations

    • Department of Urology, Stepping Hill Hospital, Stockport NHS Foundation Trust, Poplar Grove, Stockport SK2 7JE, UK
    • ,
  • Senthil K. Govindaraju

      Affiliations

    • Department of Urology, Royal Blackburn Hospital, East Lancashire Hospitals NHS Trust, Haslingden Road, Blackburn BB2 3HH, UK
    • ,
  • Patrick H. O’Reilly

      Affiliations

    • Department of Urology, Stepping Hill Hospital, Stockport NHS Foundation Trust, Poplar Grove, Stockport SK2 7JE, UK
    • ,
  • Gerald N. Collins

      Affiliations

    • Department of Urology, Stepping Hill Hospital, Stockport NHS Foundation Trust, Poplar Grove, Stockport SK2 7JE, UK
    • ,
  • Donald Neilson

      Affiliations

    • Department of Urology, Royal Blackburn Hospital, East Lancashire Hospitals NHS Trust, Haslingden Road, Blackburn BB2 3HH, UK
    • ,
  • Adebanji A.B. Adeyoju

      Affiliations

    • Department of Urology, Stepping Hill Hospital, Stockport NHS Foundation Trust, Poplar Grove, Stockport SK2 7JE, UK

Received 22 July 2008 ,Revised 12 November 2008 ,Accepted 23 November 2008.

References 

  1. England HR, Blandy JP, Paris AMI. The treatment of single and multiple papillary tumours of the bladder. In:  Macaluso P,  Smith PH,  Edsymr F editor. Bladder tumours and other topics in urological oncology. New York: Plenum Press; 1980;p. 364–462
  2. Lutzeyer W, Rubben H, Dahm H. Prognostic parameters in superficial bladder cancer: an analysis of 315 cases. Journal of Urology. 1982;127:250
  3. Newling D. Intravesical therapy in the management of superficial transitional cell carcinoma of the bladder: the experience of the EORTC GU Group. British Journal of Cancer. 1990;61(2):497–499
  4. Boyd PJ, Burnand KG. Site of bladder-tumour recurrence. Lancet. 1974;2:1290
  5. Solsona E, Iborra I, Ricos JV, Monros JL, Casanova J, Dumont R. Effectiveness of a single immediate Mitomycin C instillation in patients with low risk superficial bladder cancer: short and long-term follow up. Journal of Urology. 1999;161(2):1120–1123
  6. Hall RR, Parmar MKB, Richards AB, Smith PH. Proposals for change in cystoscopic follow up of patients with bladder cancer and adjuvant intravesical chemotherapy. British Medical Journal. 1994;308:257–260
  7. Burnand KG, Boyd PJR, Mayo ME, Shuttleworth KED, Lloyd-Davies RW. Single dose intravesical thiotepa as an adjuvant to cystodiathermy in the treatment of transitional cell bladder carcinoma. British Journal of Urology. 1976;48:55
  8. Page BH, Levison VB, Curwen MP. The site of recurrence of non-infiltrating bladder tumours. British Journal of Urology. 1978;50:237
  9. Prout GR, Koontz WW, Coombs LJ, Hawkins IR, Friedell GH National Bladder Cancer Collaborative Group A. Long-term fate of 90 patients with superficial bladder cancer randomly assigned to receive or not to receive thiotepa. Journal of Urology. 1983;130:677
  10. Tolley DA, Hargreave TB, Smith PH, Williams JL, Grigor KM, Parmar MKB, et al. Effect of intravesical Mitomycin C on recurrence of newly diagnosed superficial bladder cancer: interim report from the Medical Research Council Subgroup on Superficial Bladder Cancer (Urological Cancer Working Party). British Medical Journal. 1988;296:1759
  11. Tolley DA, Parmar MKB, Grigor KM, Lallemand G The Medical Research Council Superficial Bladder Cancer Working Party. The effect of intravesical Mitomycin C on recurrence of newly diagnosed superficial bladder cancer: a further report with 7 years of followup. Journal of Urology. 1996;155:1233–1238
  12. Devonec M, Bouvier R, Sarkissian J, Bendimerad O, Gelet A, Dubernard JM. Intravesical instillation of Mitomycin C in the prophylactic treatment of recurring superficial transitional cell carcinoma of the bladder. British Journal of Urology. 1983;55:382–385
  13. Hetherington JW, Newling DWW, Robinson MRG, Smith PH, Adib RS, Whelan P. Intravesical Mitomycin C for the treatment of recurrent superficial bladder tumours. British Journal of Urology. 1987;59:239–241
  14. Jauhiainen K, Alfthan O. Instillation of Mitomycin C and Doxorubicin in the prevention of recurrent superficial (Ta-T1) bladder cancer. British Journal of Urology. 1987;60:54–59
  15. Hamdy FC, Hastie KJ, Kerry R, Williams JL. Mitomycin C in superficial bladder cancer. Is long-term maintenance therapy worthwhile after initial treatment?. British Journal of Urology. 1993;71:183–186
  16. Clarke NS, Basu S, Prescott S, Puri R. Chemo-prevention in superficial bladder cancer using Mitomycin C: a survey of the practice patterns of British urologists. BJU International. 2006;97:716–719
  17. Kim HH, Lee C. Intravesical Mitomycin C instillation as a prophylactic treatment of superficial bladder tumor. Journal of Urology. 1989;141:1337–1340

PII: S1875-9742(08)00129-8

doi: 10.1016/j.bjmsu.2008.11.013

British Journal of Medical & Surgical Urology
Volume 2, Issue 2 , Pages 73-78 , March 2009

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